Fever is a temporary rise in body temperature, usually due to an underlying infection or illness. It is a natural immune response that helps the body fight off infections by making it less hospitable for bacteria and viruses. A normal body temperature ranges between 97°F (36.1°C) and 99°F (37.2°C), and a fever is generally considered when the temperature exceeds 100.4°F (38°C). Fever can be caused by a variety of factors, including viral and bacterial infections, inflammatory conditions, autoimmune diseases, and even certain medications or vaccinations. While mild fevers are usually harmless and resolve on their own, persistent or high fevers may indicate a more serious condition requiring medical attention.